I_Fart_Glitter

And plastic champagne glasses. And those l little headbands with the year on top.

Pretty limited compared to Xmas though.

Had a chrome book that worked just fine but unbeknownst to me had an expiration date that started counting down at its date of manufacture, not the date of purchase.

The thing worked great, but no more security updates after 3 years.

His wife:

Love herons!

Bird photography. I’m a person who tends toward depression. It was honestly very surprising the first time I noticed that when I’m photographing birds I have a huge smile on my face the whole time.

I’ve been learning the ins and outs of my camera gear for the last year and making small improvements is really satisfying. But really it’s just being out in nature, looking at adorable birds and capturing those moments for later.

Sorry, are you unable to conduct internet searches…? Or are you a troll?

Here you go dear. Maybe next time you can operate the internet machine all by yourself. I know it’s very difficult.

https://www.researchgate.net/publication/342590945_Dandelion_prevents_liver_fibrosis_inflammatory_response_and_oxidative_stress_in_rats

Background: Liver fibrosis is the main contributor to the chronic liver-associated morbidity and mortality.Purpose: The study was conducted to evaluate the effects of whole plant powder of dandelion (Taraxacumofficinale) on liver fibrosis.Methods: Liver fibrosis was induced by the oral administration of 20% carbon tetrachloride (CCL4), twice a weekfor 8 weeks. Simultaneously, dandelion root extract (500 mg/kg) was daily administered via the same route.Results: Dandelion remarkably improved the liver histology as evidenced by histopathological scoring withhematoxylin-eosin staining. Masson staining and hydroxyproline content similarly showed that dandelion decreasedcollagen deposition. Both mRNA and protein levels of α-smooth muscle actin and collagens 1 and 3 have beendecreased after dandelion treatment compared to CCL4 group. Dandelion also downregulated the mRNAexpressions of inflammatory factors interleukin-IL-1β, tumor necrosis factor-α, remodeling growth factor-β1,cyclooxygenase-2, and nuclear factor kappa-B and decreased the myeloperoxidase activity. Additionally, the effectsof dandelion were associated with the decreased levels of the hepatic oxidative stress markers (malondialdehydeand P. carbonyl) and elevation of the activity of superoxide dismutase activity. Dandelion’s effect to alleviate thefibrosis and inflammation induced by CCL4 treatment in the livers and was more pronounced than with silymarin.The total antioxidant study of dandelion extract revealed that dandelion has notable ferric reducing antioxidantpower and high total phenolic content.Conclusion: Finally, these results suggest that dandelion prevents the progression of hepatic fibrosis induced byCCL4. The dandelion’s antifibrotic effects could be attributed to its ability to scavenge free radicals and to attenuate inflammatory cells activations.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8063808/

4. Discussion In the current study, D-Gal-LPS-induced ACLF in rats with HAS-induced chronic liver failure triggered an immune-mediated liver injury with pathological serum liver marker tests and histological liver changes. The liver injuries were also associated with renal failure and systemic oxidative stress. A seven days pretreatment with TOERE reduced ACLF induced liver injury. The protecting effect of TOERE can be attributed, at least in part, to the reduction of the oxidative stress associated with immune liver injury in D-Gal-LPS-induced ACLF. Depending on the dose, the hepatoprotective effect of TOERE was similar or lower than that of SYL, an already used hepatoprotective drug. […] Because the chemical composition correlates with the pharmacological effects, TO extracts from different plant parts had different activities. Several studies demonstrated that the TO roots extract reduces alcohol-induced oxidative stress, TO leaf extract alleviates high-fat diet-induced nonalcoholic fatty liver, and TO flower extract can scavenge reactive oxygen species [22]. Similar to other studies [16,42,43], and based on the evidence of the phytochemical analysis results, our TO root extract can be considered a good natural antioxidant candidate. These results encouraged us to continue by testing the in vivo hepatoprotective and antioxidant effects of TOERE in an experimental ACLF.

https://www.sciencedirect.com/science/article/abs/pii/S0278691513002561

Obesity is an alarming public health issue because it causes a broad range of chronic diseases and metabolic syndromes, such as type 2 diabetes, cardiovascular disease, hypertension, nonalcoholic fatty liver disease (NAFLD), and insulin resistance (Zimmet et al., 2001). NAFLD is a metabolic syndrome characterized by abnormal lipid formation in hepatocytes without excess alcohol intake. The primary danger of NAFLD is that it can lead to impaired glucose metabolism, inflammatory response, and insulin resistance, which produce elevated lipogenesis of free fatty acids (FFAs) and fat accumulation in the liver (Cornier et al., 2008, Hamaguchi et al., 2005, Sarafidis and Nilsson, 2006). Excessive dietary fat intake increases the concentration of FFAs in blood and leads to elevation of triglyceride (TG) stored in liver, which causes lipid accumulation and resulting hepatic steatosis (Jang et al., 2012). Because of their safety and efficacy, and because they may possess potential bioactive components to treat or prevent the obesity and NAFLD (Jang et al., 2012, Melo et al., 2010), natural herbs and food factors have recently been the focus of many researchers. The common dandelion, Taraxacum officinale G.H. Weber ex Wiggers, a member of the Asteraceae/Composite family, is widely used as a traditional herb to treat various disorders such as liver disease, gallbladder disorders, digestive complaints, and arthritic and rheumatic diseases because of its anti-diabetic, anti-rheumatic, anti-inflammatory, anti-tumor, anti-cardiogenic and hypoglycemic properties (Bisset, 1994, Bradley, 1992, Koh et al., 2010, Racz-Kotilla et al., 1974, Schutz et al., 2005, Schutz et al., 2006). Several reports have also verified that in rodent models, dandelion inhibits oxidative stress in CCl4-induced acute liver injury, high cholesterol, streptozotocin-induced diabetes (Cho et al., 2002, Cho et al., 2003, Park et al., 2010), and fibrosis in CCl4-induced acute liver injury (Domitrovića et al., 2010). Our own recent data showed that DLE had a protective effect against liver injury induced by methionine- and choline-deficient diet in mice (Davaatseren et al., 2013). However, the underlying mechanism of DLE in preventing obesity-induced hepatic steatosis and insulin resistance remains elusive. In this study, we examined the protective effect and underlying mechanism of DLE on HFD-induced obesity. We demonstrated that DLE showed a remarkable effect on hepatic lipid accumulation and improved insulin resistance in HFD-fed mice by reducing lipid and activating phosphorylation of adenosine monophosphate (AMP)–activated protein kinase (AMPK), suggesting that DLE has a potential protective effect against NAFLD.

The leaves are a nice salad green as well. But the kind you buy at the grocery store are usually a variety of chicory named “dandelion” much like how canned pumpkin is often other squashes that are close enough to be allowed to be called pumpkin.

Dandelion is an excellent liver tonic, all parts are edible, just make sure it’s a true dandelion (there are many lookalikes if you’re not a plant person) and that the area you harvest it from isn’t treated with any pesticides, herbicides or anything like that.

California poppies ( Eschscholzia californica ) are not actually in the poppy family, their calming effect is closer to chamomile (and they don’t show up on drug tests).

You want something in the papaver family for the “beautiful flowers,” specifically papaver somniferum, but all papaver varieties have some of that compound.

Eta: they really do have “beautiful flowers”

Some would say that was Margaret Cavendish, 150 years earlier. Mary Shelly’s novels are and have been more popular though.

Agree with all of the above, would add T. Kingfisher for fantasy, Iris Murdoch for heady philosophical fiction, Agatha Christie for murder mystery, Clarissa Pinkola Estés for empowering fables and explorations of feminine archetypes, Mary Oliver for poetry, and Lady Margaret Cavendish for a great sci-fi novel from 1666.

PEMDAS bitches.